2-Fluoro-N-(5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)benzamide CAS 921890-27-9
| CAS No. | 921890-27-9 |
| Molecular Formula | C16H13FN2O3 |
| Molecular Weight | 300.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 300.28 g/mol gives 2-Fluoro-N-(5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Fluoro-N-(5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)benzamide (CAS 921890-27-9), molecular formula C16H13FN2O3 and molecular weight 300.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Fluoro-N-(5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)benzamide (C16H13FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Fluoro-N-(5-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13FN2O3 |
| Molecular Weight | 300.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 5-(5-fluoro-2-hydroxybenzoyl)-1-isopropyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 743444-77-1)
- (Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (CAS 356068-93-4)
- Methyl 2-fluoro-2-(6-fluorophenanthren-1-yl)propanoate (CAS 843614-86-8)
- 8-Fluoro-4-phenyl-4H-benzo[b][1,4]thiazine-2-carbonitrile 1,1-dioxide (CAS 1207026-39-8)
- 4-(2-Fluoro-4-nitrophenoxy)quinolin-7-ol (CAS 1394820-98-4)
- N-(7-Fluoro-3-nitro-9-oxo-9H-fluoren-2-yl)acetamide (CAS 16233-04-8)
- 4-Fluoro-3-[(imidazo[1,2-a]pyrazine-3-carbonyl)-amino]benzoic acid (CAS 2088941-83-5)
- (S)-2-[(5-Fluoro-2,4-dinitrophenyl)amino]-3-methylbutanamide (CAS 132679-61-9)
Recommended Standards
- 2,2,2-Trifluoro-1-(4-(4-methylpiperazine-1-carbonyl)phenyl)ethan-1-one (CAS 478066-72-7)
- 2-Methyl-1-phenyl-5-(trifluoromethyl)-1H-indole-3-carbonitrile (CAS 922184-60-9)
- 2-(2-Fluorophenoxy)-N-(2-oxoindolin-5-yl)acetamide (CAS 921546-43-2)
- 2-Methyl-1-phenyl-7-(trifluoromethyl)-1H-indole-3-carbonitrile (CAS 922184-61-0)
- 4-(2-Chloropropanoyl)-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 878465-62-4)
- 6H-benzo[a]phenanthridin-5-one (CAS 109648-27-3)
- 1-(1H-1,2,3-triazol-4-yl)ethan-1-one hydrochloride (CAS 1864052-48-1)
- 3-Chloropropyl benzoate (CAS 942-95-0)
- 1-Cyclopentylcyclobutane-1-carboxylic acid (CAS 1522673-27-3)
- 3-Hydroxy-1-(4-methoxyphenyl)-4-phenyl-2-azetidinone (CAS 194234-97-4)
- 1-Cyclohexyl-1H-imidazo[4,5-b]pyridine (CAS 1365094-43-4)
- 4-(3-Hydroxy-1-(3-(trifluoromethyl)phenyl)propyl)thiomorpholine 1,1-dioxide (CAS 866041-22-7)
- Ipratropium Impurity 14 (CAS CATO-C4X-166514)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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