Rivastigmine EP Impurity E CAS 923035-05-6

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.923035-05-6
Molecular FormulaC13H20N2O2
Molecular Weight236.31 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rivastigmine EP Impurity E CAS 923035-05-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 236.31 g/mol gives Rivastigmine EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Rivastigmine EP Impurity E (CAS 923035-05-6), a pharmacopoeial impurity reference standard (molecular formula C13H20N2O2, MW 236.31 g/mol) used for the identification and quantification of trace impurities in APIs.

Rivastigmine EP Impurity E (C13H20N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Rivastigmine EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H20N2O2
Molecular Weight236.31 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms2

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