1-(2,5-dimethylphenyl)-2,2,2-trifluoroethanol CAS 923137-56-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2,5-dimethylphenyl)-2,2,2-trifluoroethanol.

1-(2,5-dimethylphenyl)-2,2,2-trifluoroethanol (CAS 923137-56-8) is a high-purity analytical reference standard with the molecular formula C10H11F3O and a molecular weight of 204.19 g/mol.

Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 1-(2,5-dimethylphenyl)-2,2,2-trifluoroethanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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