4-(Thiophen-2-ylsulfonyl)piperazin-2-one CAS 923142-46-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Thiophen-2-ylsulfonyl)piperazin-2-one.

CATO supplies 4-(Thiophen-2-ylsulfonyl)piperazin-2-one (CAS 923142-46-5), a certified reference material (molecular formula C8H10N2O3S2, MW 246.31 g/mol) for analytical method development and quality control.

4-(Thiophen-2-ylsulfonyl)piperazin-2-one (C8H10N2O3S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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