2-(4-Chloro-2-nitrophenyl)-2-oxoacetic acid CAS 923548-29-2
| CAS No. | 923548-29-2 |
| Molecular Formula | C8H4ClNO5 |
| Molecular Weight | 229.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Chloro-2-nitrophenyl)-2-oxoacetic acid.
2-(4-Chloro-2-nitrophenyl)-2-oxoacetic acid (CAS 923548-29-2), molecular formula C8H4ClNO5 and molecular weight 229.57 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-Chloro-2-nitrophenyl)-2-oxoacetic acid (C8H4ClNO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Chloro-2-nitrophenyl)-2-oxoacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4ClNO5 |
| Molecular Weight | 229.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 6-Nitro-1,3-benzodioxole-5-carbonyl chloride (CAS 50425-29-1)
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- 1-(BROMOMETHYL)-2-CHLORO-4-FLUOROBENZENE 2-Chloro-4-fluorobenzyl bromide 45767-66-6 ALPHA-BROMO-2-CHLORO-4-FLUOROTOLUENE AS00679 TIMTEC-BB SBB005762 (CAS 45767-66-6)
- 2-(Chlorofluoromethyl)-6-nitro-1H-benzo[d]imidazole (CAS 1309602-41-2)
- 7-Chloro-8-methyl-2-pyridin-4-ylquinoline-4-carbonyl chloride hydrochloride (CAS 1332530-76-3)
- 2-Amino-4-(4-chlorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 107753-00-4)
- LY 2119620 (CAS 886047-22-9)
- 1-(5-((3,5-Dichlorophenyl)thio)-4-nitrothiophen-2-yl)ethanone (CAS 1247819-69-7)
- 5-Chloro-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 113075-74-4)
- Ethyl 2-amino-3,5-dibromobenzoate (CAS 353754-49-1)
- 4-Chlorothiazole-2-sulfonyl chloride (CAS 89501-96-2)
- n-(3-Methoxybenzyl)-1,2,3,4-tetrahydronaphthalen-1-amine hydrobromide (CAS 1609399-86-1)
- 6-Methoxy-2-methyl-3-nitrobenzoic acid (CAS 474454-46-1)
- Semaglutide Impurity 122 (CAS CATO-C4X-2226122)
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