(3S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluorophenyl)piperidine-3-carboxylic acid CAS 923932-21-2
| CAS No. | 923932-21-2 |
| Molecular Formula | C17H22FNO4 |
| Molecular Weight | 323.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (3S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluorophenyl)piperidine-3-carboxylic acid (CAS 923932-21-2), a certified reference material (molecular formula C17H22FNO4, MW 323.36 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (3S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluorophenyl)piperidine-3-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 323.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H22FNO4 |
| Molecular Weight | 323.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3R,4S)-1-(tert-butoxycarbonyl)-4-(5-fluoro-2-methylphenyl)pyrrolidine-3-carboxylic acid (CAS 2227905-44-2)
- (4-(2-Fluorophenyl)piperazin-1-yl)(1H-indol-2-yl)methanone (CAS 919729-68-3)
- (3R,4S)-1-(tert-butoxycarbonyl)-4-(4-fluoro-2-methylphenyl)pyrrolidine-3-carboxylic acid (CAS 957476-24-3)
- (R)-1-(tert-butoxycarbonyl)-2-(2-fluorobenzyl)pyrrolidine-2-carboxylic acid (CAS 959576-66-0)
- [S(R)]-N-[(R)-[2-(Diphenylphosphino)phenyl]-1-naphthalenylmethyl]-2-methyl-2-propanesulfinamide (CAS 1616688-65-3)
- (S)-4-Benzyl-3-(pent-4-enoyl)oxazolidin-2-one (CAS 104266-88-8)
- 2-Oxoimidazolidine-1-carbohydrazide (CAS 64341-24-8)
- (5-Phenyl-1,2,4-oxadiazol-3-yl)methanol (CAS 73217-37-5)
- 4-Biphenylmethanol (CAS 3597-91-9)
- 1-(3-(Difluoromethoxy)phenyl)cyclopropan-1-amine (CAS 1266159-47-0)
- 1-Methyl-1H-pyrazole-3,5-diamine (CAS 16675-35-7)
- N-(2-Carbamoylbenzofuran-3-yl)-1-ethyl-1H-pyrazole-5-carboxamide (CAS 1170395-11-5)
- 4-Nitrosoaniline (CAS 659-49-4)
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