3-(2-Bromophenyl)-5-methylisoxazole-4-carboxylic acid CAS 92545-84-1
| CAS No. | 92545-84-1 |
| Molecular Formula | C11H8BrNO3 |
| Molecular Weight | 282.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(2-Bromophenyl)-5-methylisoxazole-4-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(2-Bromophenyl)-5-methylisoxazole-4-carboxylic acid (CAS 92545-84-1), a certified reference material (molecular formula C11H8BrNO3, MW 282.09 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2-Bromophenyl)-5-methylisoxazole-4-carboxylic acid (C11H8BrNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(2-Bromophenyl)-5-methylisoxazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8BrNO3 |
| Molecular Weight | 282.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromophenyl Standards
- Methyl 5-(2-bromophenyl)-1,2-oxazole-3-carboxylate (CAS 1053657-05-8)
- 2-(2-Bromophenyl)-5-methyloxazole-4-carboxylic acid (CAS 1140626-84-1)
- Methyl 2-(4-bromophenyl)oxazole-5-carboxylate (CAS 1206984-00-0)
- 1-[(3-Bromophenyl)methyl]-3-nitro-1h-pyrazole (CAS 1240567-36-5)
- 1-[(2-Bromophenyl)methyl]-3-nitro-1h-pyrazole (CAS 1240567-60-5)
- 1-[(2-Bromophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1240568-81-3)
- 5-(3-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 1373223-21-2)
- 5-(4-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 1373223-59-6)
Recommended Standards
- 2-Bromo-3-(1,3-dioxoisoindolin-2-yl)propanal (CAS 325488-75-3)
- 3-(3-Bromophenyl)-5-methyl-1,2-oxazole-4-carboxylic acid (CAS 954230-35-4)
- 2-(6-Bromo-5-methyl-3-indolyl)-2-oxoacetic Acid (CAS 2097800-21-8)
- 3-(4-Bromophenyl)-5-methylisoxazole-4-carboxylic acid (CAS 91182-58-0)
- 2-Bromo-5-(4-chlorophenyl)-1,3,4-oxadiazole, 97% (CAS 1368558-17-1)
- 1-[3-(aminomethyl)phenyl]ethan-1-one hydrochloride (CAS 149889-64-5)
- 2-(2-Benzoylphenyl)-2-phenylacetonitrile (CAS 127667-32-7)
- N4-Allyl-6-chloropyrimidine-4,5-diamine (CAS 181304-94-9)
- Mespirenone (CAS 87952-98-5)
- (4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-acetic acid (CAS 1060794-98-0)
- 3-(Thiophen-3-yl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603068-09-3)
- N-(3,4-Difluorophenyl)-2-[(4-{[4-({[(3,4-difluorophenyl)carbamoyl]methyl}sulfanyl)phenyl]sulfanyl}phenyl)sulfanyl]acetamide (CAS 882079-76-7)
- (cis-Hexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)(pyrrolidin-1-yl)methanone (CAS 1538593-53-1)
- Semaglutide impurity 103 (CAS 1446013-07-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com