Methyl 2-(5-bromo-2-cyanophenyl)-2-cyanoacetate CAS 925672-87-3

Purity 97%+In StockPharmaceutical Standards
CAS No.925672-87-3
Molecular FormulaC11H7BrN2O2
Molecular Weight279.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 2-(5-bromo-2-cyanophenyl)-2-cyanoacetate CAS 925672-87-3 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Methyl 2-(5-bromo-2-cyanophenyl)-2-cyanoacetate (CAS 925672-87-3), molecular formula C11H7BrN2O2 and molecular weight 279.09 g/mol, is a CATO reference standard with documented purity and traceability.

Methyl 2-(5-bromo-2-cyanophenyl)-2-cyanoacetate (C11H7BrN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), Methyl 2-(5-bromo-2-cyanophenyl)-2-cyanoacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H7BrN2O2
Molecular Weight279.09 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentBr-containing
Nitrogen Atoms2

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