[3-chloro-4-(difluoromethoxy)-5-methoxyphenyl]methanol CAS 926183-97-3
| CAS No. | 926183-97-3 |
| Molecular Formula | C9H9ClF2O3 |
| Molecular Weight | 238.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
[3-chloro-4-(difluoromethoxy)-5-methoxyphenyl]methanol (CAS 926183-97-3) is a high-purity analytical reference standard with the molecular formula C9H9ClF2O3 and a molecular weight of 238.62 g/mol.
[3-chloro-4-(difluoromethoxy)-5-methoxyphenyl]methanol (C9H9ClF2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9ClF2O3 |
| Molecular Weight | 238.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related chloro Standards
- 2-[4-chloro-3-(difluoromethyl)-5-methyl-1h-pyrazol-1-yl]propanoic acid (CAS 1005584-35-9)
- 5-Chloro-2-(trifluoromethylthio) nicotinonitrile (CAS 1204234-33-2)
- 4-Chloro-7-methoxy-2-oxo-2H-chromene-3-carbaldehyde (CAS 122978-33-0)
- 6-Chloro-3-methyl-4-oxo-4H-chromene-2-carboxylic Acid (CAS 1239779-74-8)
- 4-(3-Chloro-2,4-difluorophenyl)-1H-pyrrole-3-carbonitrile (CAS 124185-27-9)
- 4-Chloro-2-(trifluoromethyl)thieno[3,2-d]pyrimidine (CAS 147972-27-8)
- Ethyl 4-chloro-1-(2,2-difluoroethyl)-1H-pyrazole-3-carboxylate (CAS 1856061-98-7)
- 2-chloro-4-(fluorosulfonyl)benzoic acid (CAS 1934852-61-5)
Recommended Standards
- 2-cHloro-5-(fluorosulfonyl)benzoic acid (CAS 21346-66-7)
- 3-(Chlorosulfonyl)-2-fluorobenzoic acid (CAS 1909327-45-2)
- 2-Chloro-6-(trifluoromethyl)thiazolo[4,5-b]pyridine (CAS 884860-62-2)
- 2-Chloro-6-(trifluoromethyl)thiazolo[5,4-b]pyridine (CAS 99520-99-7)
- 2,2,3,3-Tetrafluoropropanoic anhydride (CAS 337-83-7)
- Benzyl 4-(3-aminoazetidin-1-yl)piperidine-1-carboxylate dihydrochloride (CAS 1179362-99-2)
- 5-[2-(2-Naphthyloxy)phenyl]-2H-tetrazole (CAS 1305320-61-9)
- 3-Methyl-2,6-diphenylpiperidin-4-one (CAS 5554-57-4)
- 2,2'-[1,4-Phenylenebis(oxy)]bis-propanoic Acid Dimethyl Ester (CAS 85977-51-1)
- Methyl 2-[2-(4-bromobenzenesulfonamido)acetamido]-2-phenylacetate (CAS 1100757-01-4)
- 2-(1H-Pyrrol-1-yl)phenyl 4-methylbenzoate (CAS 339098-77-0)
- 1,1,1-trifluoro-3-(1-phenyl-1H-1,2,3,4-tetraazol-5-yl)-4-tetrahydro-1H-pyrrol-1-ylbut-3-en-2-one (CAS 152427-06-0)
- Ethyl 3-(4-nitrobenzamido)-2-oxo-6-phenyl-2H-pyran-5-carboxylate (CAS 338418-35-2)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com