[2-(difluoromethoxy)-3-methoxyphenyl]methanol CAS 926188-34-3

Purity 97%+In StockPharmaceutical Standards
CAS No.926188-34-3
Molecular FormulaC9H10F2O3
Molecular Weight204.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

[2-(difluoromethoxy)-3-methoxyphenyl]methanol CAS 926188-34-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [2-(difluoromethoxy)-3-methoxyphenyl]methanol.

CATO supplies [2-(difluoromethoxy)-3-methoxyphenyl]methanol (CAS 926188-34-3), a certified reference material (molecular formula C9H10F2O3, MW 204.17 g/mol) for analytical method development and quality control.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, [2-(difluoromethoxy)-3-methoxyphenyl]methanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H10F2O3
Molecular Weight204.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing

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