2-[4-(4-fluorophenyl)-5-methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl]acetic acid CAS 926193-45-5
| CAS No. | 926193-45-5 |
| Molecular Formula | C12H10FNO3S |
| Molecular Weight | 267.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[4-(4-fluorophenyl)-5-methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl]acetic acid.
2-[4-(4-fluorophenyl)-5-methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl]acetic acid (CAS 926193-45-5) is a high-purity analytical reference standard with the molecular formula C12H10FNO3S and a molecular weight of 267.28 g/mol.
The molecular framework of 2-[4-(4-fluorophenyl)-5-methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl]acetic acid (C12H10FNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-[4-(4-fluorophenyl)-5-methyl-2-oxo-2,3-dihydro-1,3-thiazol-3-yl]acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10FNO3S |
| Molecular Weight | 267.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related fluorophenyl Standards
- N-(4-fluorophenyl)-4-hydroxybenzene-1-sulfonamide (CAS 1082560-58-4)
- 2-[(2-Fluorophenyl)amino]pyridine-3-sulfonamide (CAS 1340757-38-1)
- Ethyl 2-(3-fluorophenyl)-4-hydroxythiazole-5-carboxylate (CAS 1445752-14-6)
- Ethyl 2-(4-fluorophenyl)-4-hydroxythiazole-5-carboxylate (CAS 1445752-15-7)
- 4-(2-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine (CAS 1710293-73-4)
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- 2-{[5-(2-fluorophenyl)-4-methyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 731003-94-4)
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Recommended Standards
- 2-[2-(Piperazin-1-yl)-ethyl]-1,3-dioxolan (CAS 25553-77-9)
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- 2-{[(tert-butoxy)carbonyl]amino}-2-(2-hydroxyphenyl)acetic acid (CAS 55477-47-9)
- Methyl (2S,4S)-4-[(cyclopropylcarbonyl)oxy]-2-pyrrolidinecarboxylate hydrochloride (CAS 1354486-91-1)
- 4,5,6,7-Tetrahydro-1H-pyrazolo[3,4-b]pyridine (CAS 933734-43-1)
- 5-[(4-fluorophenyl)methyl]-1,2,4-thiadiazol-3-amine (CAS 1343928-91-5)
- (4-Chlorophenyl)(prop-2-yn-1-yl)sulfane (CAS 17277-23-5)
- 3-(Thiomorpholinomethyl)benzenethiol (CAS 1379344-04-3)
- Telmisartan Impurity 18 (CAS 2031272-32-7)
- 4-(Dimethylamino)-N-(2-(2-phenylpyrimidin-5-yl)ethyl)benzamide (CAS 2034512-72-4)
- 6-Iodohexyl acetate (CAS 77295-58-0)
- 2-Chloro-4-fluoronicotinoyl chloride (CAS 1448155-98-3)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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