2'-(Trifluoromethoxy)-2-(trifluoromethyl)-[1,1'-biphenyl]-4-amine CAS 926221-31-0

Purity 97%+In StockPharmaceutical Standards
CAS No.926221-31-0
Molecular FormulaC14H9F6NO
Molecular Weight321.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2'-(Trifluoromethoxy)-2-(trifluoromethyl)-[1,1'-biphenyl]-4-amine CAS 926221-31-0 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2'-(Trifluoromethoxy)-2-(trifluoromethyl)-[1,1'-biphenyl]-4-amine (CAS 926221-31-0), molecular formula C14H9F6NO and molecular weight 321.22 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2'-(Trifluoromethoxy)-2-(trifluoromethyl)-[1,1'-biphenyl]-4-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 321.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H9F6NO
Molecular Weight321.22 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms1

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