1-(4-Chloro-2-fluorobenzoyl)piperazine CAS 926227-66-9
| CAS No. | 926227-66-9 |
| Molecular Formula | C11H12ClFN2O |
| Molecular Weight | 242.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-Chloro-2-fluorobenzoyl)piperazine (C11H12ClFN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1-(4-Chloro-2-fluorobenzoyl)piperazine (CAS 926227-66-9), a certified reference material (molecular formula C11H12ClFN2O, MW 242.68 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-Chloro-2-fluorobenzoyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12ClFN2O |
| Molecular Weight | 242.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-[(4-chloro-1h-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid (CAS 1006455-24-8)
- 4-[(4-chloro-1h-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid (CAS 1006485-93-3)
- 1-(2-Chloro-6-fluorobenzoyl)piperazine (CAS 1016491-13-6)
- 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylic acid (CAS 1047630-55-6)
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Recommended Standards
- 1-(2-Chloro-4-fluorobenzoyl)piperazine (CAS 926257-29-6)
- 1-Chloro-7-isoquinolinesulphonamide (CAS 223671-78-1)
- (5-Chloro-2-fluorophenyl)(piperazin-1-yl)methanone (CAS 926238-77-9)
- 2-((3-Chloro-4-fluorophenyl)amino)-N-cyclopropylacetamide (CAS 923191-44-0)
- PU-H71 Trifluoroacetic AcidDiscontinued (CAS 873436-91-0)
- Ruthenium(1+), (η6-benzene)[1,1'-(1R)-[1,1'-binaphthalene]-2,2'-diylbis[1,1-bis(4-methylphenyl)phosphine-κP]]chloro-, chloride (CAS 854274-96-7)
- Methyl 2-(2-bromo-5-methoxyphenyl)acetate (CAS 117565-90-9)
- 6,7-Dimethoxy-1,1-dimethyl-1,2,3,4-tetrahydroisoquinoline (CAS 249624-85-9)
- 1-(3-Fluorophenyl)cyclobutanecarboxylic Acid (CAS 179411-84-8)
- Ethyl 2-(2-(aminomethyl)phenyl)acetate (CAS 94286-13-2)
- 3-Amino-2-hydroxy-3-methylbutanoic acid (CAS 62000-66-2)
- 1-(Pyrimidin-2-yl)-1,4-diazepane (CAS 21279-57-2)
- 5',5''''-([2,2'-Bithiophene]-5,5'-diyl)bis(([1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid)) (CAS 1227780-71-3)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
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