2-Amino-2-(2,6-difluorophenyl)acetonitrile CAS 926233-91-2
| CAS No. | 926233-91-2 |
| Molecular Formula | C8H6F2N2 |
| Molecular Weight | 168.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Amino-2-(2,6-difluorophenyl)acetonitrile (C8H6F2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 2-Amino-2-(2,6-difluorophenyl)acetonitrile (CAS 926233-91-2), a certified reference material (molecular formula C8H6F2N2, MW 168.14 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Amino-2-(2,6-difluorophenyl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F2N2 |
| Molecular Weight | 168.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-amino-2-(2,5-difluorophenyl)acetonitrile (CAS 124777-80-6)
- 5-Amino-2-(trifluoromethyl)thiazole (CAS 1367944-72-6)
- 2-Amino-5-(trifluoromethyl)thiazole (CAS 169260-97-3)
- 2-Amino-2-(2,4-difluorophenyl)acetonitrile (CAS 189138-13-4)
- 2-Amino-2-(3,4-difluorophenyl)acetonitrile (CAS 218449-30-0)
- 3-Amino-5-(difluoromethyl)benzonitrile (CAS 2438163-01-8)
- 4-Amino-2-(difluoromethyl)benzonitrile (CAS 2275752-93-5)
- 5-Amino-7-fluorobenzo[d]oxazol-2-ol (CAS 1267629-05-9)
Recommended Standards
- 2,7-difluoro-1-methyl-1H-1,3-benzodiazole (CAS 2298034-46-3)
- 2,6-difluoro-1-methyl-1H-1,3-benzodiazole (CAS 2297028-52-3)
- 3-(2,4-difluorophenyl)prop-2-enal (CAS 883107-63-9)
- 2,5-difluoro-1-methyl-1H-1,3-benzodiazole (CAS 2300798-99-4)
- 3-Amino-4-(4-chlorophenyl)-6-phenyl-N-(2-(trifluoromethyl)phenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 337489-03-9)
- 1,2,3,7,8,9-Hexachlorodibenzo-p-Dioxin (CAS 19408-74-3)
- 1-Methyl-1H-pyrrole (CAS 96-54-8)
- Quinoline-D7 (CAS 34071-94-8)
- 9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid (CAS 51991-93-6)
- 2,3-Dimethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid (CAS 1544437-41-3)
- 2-nitro-4-(pyridin-4-yl)aniline (CAS 59656-62-1)
- Prednisolone Impurity 36 (CAS CATO-C4X-173736)
- 4-Fluoro-2-mercaptobenzoic acid (CAS 81223-43-0)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
Why CATO?
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