2-[1-(2,4-difluorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid CAS 926239-71-6
| CAS No. | 926239-71-6 |
| Molecular Formula | C13H12F2N2O2 |
| Molecular Weight | 266.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[1-(2,4-difluorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid.
2-[1-(2,4-difluorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid (CAS 926239-71-6), molecular formula C13H12F2N2O2 and molecular weight 266.24 g/mol, is a CATO reference standard with documented purity and traceability.
2-[1-(2,4-difluorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid (C13H12F2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-[1-(2,4-difluorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12F2N2O2 |
| Molecular Weight | 266.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related difluorophenyl Standards
- Ethyl 5-(3,4-difluorophenyl)-1-methyl-1H-pyrazole-3-carboxylate (CAS 1170363-38-8)
- Ethyl 5-(2,6-difluorophenyl)-1-methyl-1h-pyrazole-3-carboxylate (CAS 1361019-08-0)
- 2-(1-(3,4-Difluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl)acetic acid (CAS 1416343-09-3)
- Ethyl 1-(2,4-difluorophenyl)-5-methyl-1H-pyrazole-4-carboxylate (CAS 175135-71-4)
- (4E)-2-(2,6-Difluorophenyl)-4-[1-(dimethylamino)ethylidene]-4,5-dihydro-1,3-oxazol-5-one (CAS 866010-20-0)
- 3-(2,6-Difluorophenyl)-1-methyl-1h-pyrazole-5-carboxylic acid ethyl ester (CAS 668969-40-2)
- 1-(2,4-Difluorophenyl)-3-(1,3-dimethyl-1H-pyrazol-5-yl)urea (CAS 690626-57-4)
- (2,4-Difluorophenyl)(3-fluoro-4-methoxyphenyl)methanone (CAS 1154186-23-8)
Recommended Standards
- 2,5-Difluoro-3,6-dimercaptoterephthalic acid (CAS 2089430-11-3)
- 2-(Methylsulfonyl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one (CAS 386715-52-2)
- 3-(Thiophen-2-yl)-3-(2,2,2-trifluoroacetamido)propanamide (CAS 861209-46-3)
- 2-(Methylsulfonyl)-1-(2-(trifluoromethyl)phenyl)ethan-1-one (CAS 387350-34-7)
- 2-(6-Bromopyridin-3-yl)-2-methylpropan-1-ol (CAS 1240596-24-0)
- 1-(3-Amino-3-(difluoromethyl)azetidin-1-yl)ethan-1-one hydrochloride (CAS 2875097-14-4)
- Tert-butyl (1-(ethylcarbamoyl)piperidin-4-yl)carbamate (CAS 1188964-80-8)
- Methyl 1,4-diazabicyclo[2.2.2]Octane-2-carboxylate (CAS 29924-68-3)
- 7-(4-Fluorophenyl)-2-(1H-pyrrol-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 338953-46-1)
- 5-Bromo-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1215621-14-9)
- 1-Bromo-5-fluoro-2-methylnaphthalene (CAS 925442-82-6)
- Benzyl 4-(((1r,4r)-4-(guanidinomethyl)cyclohexanecarbonyl)oxy)benzoate hydrochloride (CAS 78718-46-4)
- 1,3-Bis(perfluorophenyl)urea (CAS 21132-30-9)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
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