(2Z)-3-[1-(3-amino-3-oxopropyl)-3-(3,4-difluorophenyl)-1H-pyrazol-4-yl]-2-cyanoacrylic acid CAS 926241-08-9
| CAS No. | 926241-08-9 |
| Molecular Formula | C16H12F2N4O3 |
| Molecular Weight | 346.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2Z)-3-[1-(3-amino-3-oxopropyl)-3-(3,4-difluorophenyl)-1H-pyrazol-4-yl]-2-cyanoacrylic acid (CAS 926241-08-9) is a high-purity analytical reference standard with the molecular formula C16H12F2N4O3 and a molecular weight of 346.29 g/mol.
(2Z)-3-[1-(3-amino-3-oxopropyl)-3-(3,4-difluorophenyl)-1H-pyrazol-4-yl]-2-cyanoacrylic acid (C16H12F2N4O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12F2N4O3 |
| Molecular Weight | 346.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Z Standards
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Recommended Standards
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- 4-Bromo-2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-1-nitrobenzene (CAS 1621961-83-8)
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- 1,7-Diphenyl-4-hepten-3-one (CAS 79559-59-4)
- Tert-butyl (2S,3S)-3-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate (CAS 2306246-71-7)
- 2-Bromo-5-chloro-4-cyclopropoxypyridine (CAS 1243447-72-4)
- Paricalcitol Impurity 23 (CAS CATO-C4X-138723)
- 5,6'-Dichloro-2,3'-bipyridine (CAS 1125410-06-1)
- 4-(2,5-Dichlorothiophen-3-yl)-4-oxobutanoic acid (CAS 19945-43-8)
- 4-Bromo-N-cyclohexyl-3-(trifluoromethyl)benzenesulfonamide (CAS 1020253-02-4)
- 3-(m-tolyl)-[1,2,4]Triazolo[3,4-b][1,3,4]thiadiazol-6-amine (CAS 629652-21-7)
- 1-[3-(prop-2-yn-1-yloxy)phenyl]ethan-1-one (CAS 34264-13-6)
- Protein Kinase C (19-36) Peptide (CAS 113731-96-7)
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