4-(1h-1,2,4-Triazol-1-yl)-2-(trifluoromethyl)aniline CAS 926244-75-9
| CAS No. | 926244-75-9 |
| Molecular Formula | C9H7F3N4 |
| Molecular Weight | 228.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(1h-1,2,4-Triazol-1-yl)-2-(trifluoromethyl)aniline.
4-(1h-1,2,4-Triazol-1-yl)-2-(trifluoromethyl)aniline (CAS 926244-75-9), molecular formula C9H7F3N4 and molecular weight 228.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(1h-1,2,4-Triazol-1-yl)-2-(trifluoromethyl)aniline (C9H7F3N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7F3N4 |
| Molecular Weight | 228.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related h Standards
- 4-(2H-1,2,3-triazol-2-yl)-2-(trifluoromethyl)aniline (CAS 1087792-57-1)
- 3-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethyl)aniline (CAS 1220630-55-6)
- 3-(4H-1,2,4-triazol-4-yl)-5-(trifluoromethyl)aniline (CAS 1220630-92-1)
- 3-(1h-1,2,4-Triazol-3-yl)-5-(trifluoromethyl)aniline (CAS 1249956-08-8)
- 2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethyl)aniline (CAS 438019-67-1)
- 4-(1h-1,2,4-Triazol-1-yl)-3-(trifluoromethyl)aniline (CAS 351325-27-4)
- 2-((1H-1,2,4-Triazol-3-yl)amino)quinazolin-4(1H)-one (CAS 61741-45-5)
- 2-((1H-1,2,4-Triazol-5-yl)methyl)isoindoline-1,3-dione (CAS 95074-14-9)
Recommended Standards
- 3-[3-(trifluoromethyl)phenyl]-1h-1,2,4-triazol-5-amine (CAS 502686-01-3)
- 3-(p-Tolyl)-5-(trifluoromethyl)-1,2,4-oxadiazole (CAS 680215-58-1)
- 4-(4-(Trifluoromethyl)phenyl)oxazol-2-amine (CAS 859721-53-2)
- 3-(4-(Trifluoromethoxy)phenyl)-1H-pyrazole (CAS 474707-71-6)
- 3-(1-Pyrrolidinylmethyl)benzonitrile (CAS 321198-27-0)
- (E)-3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)acrylic acid (CAS 387350-55-2)
- 8-Bromo-5-methylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1427448-35-8)
- (3-Bromophenyl)(4-chloro-3,5-dimethylphenyl)methanol (CAS 1443351-75-4)
- 2-(3-Bromofuran-2-yl)butanoic acid (CAS 1491986-08-3)
- N-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-2-(naphthalen-1-yl)acetamide (CAS 164299-69-8)
- (1R,2S,4S)-7-oxabicyclo[2.2.1]Heptane-2-carbonitrile (CAS 1727-96-4)
- 3-Octanol (CAS 589-98-0)
- cis-3,4',5-Trimethoxy-3'-aminostilbene (CAS 586410-12-0)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com