5-Methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1h-pyrazole-4-carboxylic acid CAS 926247-69-0
| CAS No. | 926247-69-0 |
| Molecular Formula | C11H8F3N3O2 |
| Molecular Weight | 271.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1h-pyrazole-4-carboxylic acid (CAS 926247-69-0) is a high-purity analytical reference standard with the molecular formula C11H8F3N3O2 and a molecular weight of 271.20 g/mol.
5-Methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1h-pyrazole-4-carboxylic acid (C11H8F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1h-pyrazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8F3N3O2 |
| Molecular Weight | 271.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-1,2,4-triazole-3-carboxylic acid (CAS 103058-77-1)
- 5-Methyl-1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1097070-53-5)
- 5-Methyl-1-(2-(trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1097070-54-6)
- methyl 1-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazole-3-carboxylate (CAS 1170420-43-5)
- 5-Methyl-2-(2-(trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431727-76-2)
- 1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethan-1-amine (CAS 290297-43-7)
- 1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethanamine (CAS 511256-36-3)
- 1-(3,5-Bis(trifluoromethyl)phenyl)propan-1-amine (CAS 685503-45-1)
Recommended Standards
- 5-Methyl-1-(4-nitrophenyl)-3-(trifluoromethyl)-1H-pyrazole (CAS 374814-09-2)
- 5-Methyl-2-(3-(trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 241797-98-8)
- 5-Methyl-1-(3-(trifluoromethyl)phenyl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 499771-21-0)
- Dimethyl 2-(3-fluoro-2-nitrophenyl)propanedioate (CAS 872141-24-7)
- 2-Chloro-1-(2-((isopropyl(methyl)amino)methyl)pyrrolidin-1-yl)ethanone (CAS 1353958-64-1)
- 5-(5-Bromo-2-fluorophenoxy)pentanenitrile (CAS 1443347-81-6)
- 6-Fluoro-3-iodo-1-methyl-1H-indazole (CAS 1257535-15-1)
- 4-Ethoxy-1-ethyl-2-fluorobenzene (CAS 2385841-28-9)
- 4-Bromo-2-fluoro-3-methoxyphenol (CAS 1779753-99-9)
- 2-(6-Amino-1h-indol-1-yl)ethan-1-ol (CAS 1095507-56-4)
- 4-Bromo-5-(4-nitrophenyl)-1H-imidazole (CAS 67453-40-1)
- (2-Morpholinothiazol-4-yl)methanamine (CAS 1023811-09-7)
- 4-Chloro-3-fluoro-5-formylbenzoic acid (CAS 2384550-77-8)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com