2-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide CAS 926257-28-5
| CAS No. | 926257-28-5 |
| Molecular Formula | C9H8F3NO2 |
| Molecular Weight | 219.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide (CAS 926257-28-5), a certified reference material (molecular formula C9H8F3NO2, MW 219.16 g/mol) for analytical method development and quality control.
2-Hydroxy-N-[4-(trifluoromethyl)phenyl]acetamide (C9H8F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H8F3NO2 |
| Molecular Weight | 219.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 4-Hydroxy-N-(2,2,2-trifluoroethyl)benzamide (CAS 1019343-45-3)
- 5-Hydroxy-N-methyl-2-(trifluoromethyl)benzamide (CAS 1243280-39-8)
- 2-Hydroxy-N-methyl-5-(trifluoromethyl)benzamide (CAS 1243361-01-4)
- 4-Hydroxy-N-methyl-3-(trifluoromethyl)benzamide (CAS 1243392-58-6)
- 3-Hydroxy-N-methyl-5-(trifluoromethyl)benzamide (CAS 862541-37-5)
- N-(4-Hydroxy-2-(trifluoromethyl)phenyl)acetamide (CAS 821764-98-1)
- 6-hydroxy-5-sulfopyridine-3-carboxylic acid (CAS 1443980-09-3)
- 2-Hydroxy-3-nitronaphthalene-1,4-dione (CAS 54808-30-9)
Recommended Standards
- 2-Amino-6-methyl-4-(trifluoromethyl)pyridine-3-carboxamide (CAS 78451-28-2)
- 2-Methoxy-4-(trifluoromethyl)benzamide (CAS 886500-54-5)
- 2-Amino-3-methyl-4-(trifluoromethyl)benzoic acid (CAS 851045-51-7)
- 2-Methoxy-5-(trifluoromethyl)benzamide (CAS 874804-06-5)
- 3-(3-Methoxyphenyl)-1-(p-tolyl)-1H-pyrazole-4-carboxylic acid (CAS 956386-76-8)
- 2-Chloro-4,5-difluorobenzaldehyde (CAS 165047-23-4)
- 1-Bromo-4-((2,2-difluorocyclopropyl)methoxy)benzene (CAS 1353776-92-7)
- 3-(Perfluoroethoxy)aniline (CAS 717-84-0)
- 6-chloro-2-methyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 129689-05-0)
- 2-[Bis[(tert-butyloxy)carbonyl]amino]-3-nitrobenzoic Acid Methyl Ester (CAS 342794-46-1)
- 5-(4-Isopropoxybenzoyl)-2-methylpyridine (CAS 1187164-63-1)
- 1-Hydroxy Pioglitazone Hydrochloride (CAS 146062-46-6)
- Z-Leu-Leu-4,5-dehydro-Leu-aldehyde (CAS 181139-85-5)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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