4-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-benzoic acid CAS 926257-72-9

Purity 97%+In StockPharmaceutical Standards
CAS No.926257-72-9
Molecular FormulaC12H11ClN2O2
Molecular Weight250.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-benzoic acid CAS 926257-72-9 chemical structure

Description

4-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-benzoic acid (CAS 926257-72-9), molecular formula C12H11ClN2O2 and molecular weight 250.68 g/mol, is a CATO reference standard with documented purity and traceability.

4-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-benzoic acid (C12H11ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(4-Chloro-3,5-dimethyl-pyrazol-1-yl)-benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H11ClN2O2
Molecular Weight250.68 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms2

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