Nemonoxacin Impurity 98 CAS 926279-66-5
| CAS No. | 926279-66-5 |
| Molecular Formula | C15H14FNO4 |
| Molecular Weight | 291.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Nemonoxacin Impurity 98 (CAS 926279-66-5, C15H14FNO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Nemonoxacin Impurity 98 (C15H14FNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nemonoxacin Impurity 98 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14FNO4 |
| Molecular Weight | 291.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nemonoxacin Standards
- Nemonoxacin Impurity 69 (CAS CATO-C4X-312869)
- Nemonoxacin Impurity 40 (CAS CATO-C4X-312840)
- Nemonoxacin Impurity 101 (CAS CATO-C4X-3128101)
- Nemonoxacin Impurity 28 (CAS 951163-63-6)
- Nemonoxacin Impurity 71 (CAS 1203651-06-2)
- Nemonoxacin Impurity 53 (CAS CATO-C4X-312853)
- Nemonoxacin Impurity 54 (CAS 269407-02-5)
- Nemonoxacin Impurity 25 (CAS 221221-15-4)
Recommended Standards
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