5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine hydrochloride CAS 927887-18-1
| CAS No. | 927887-18-1 |
| Molecular Formula | C14H17IN4O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine hydrochloride (CAS 927887-18-1), molecular formula C14H17IN4O2HCl and molecular weight 436.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine hydrochloride (C14H17IN4O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17IN4O2 HCl |
| Molecular Weight | 436.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 4 |
Related Iodo Standards
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Recommended Standards
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- 2-(4-Chlorophenoxy)-2-((5-chloropyrimidin-2-yl)oxy)-1-phenylethanone (CAS 88350-63-4)
- α-Cyano-4-hydroxycinnamic acid-d<SUB>7</SUB> (CAS 1173097-47-6)
- 3',6'-Diamino-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one (CAS 509-72-8)
- 2,3,5,6,alpha,alpha,alpha-Heptafluoro-p-toluidine 2,3,5,6-tetrafluoro-4-(trifluoromethyl)aniline 2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenylamine 2,3,5,6-tetrafluoro-4-trifluoromethyl-phenylamine 4 - Amino - heptafluorotoluene 4-amino-2,3,5,6-tetrafluorobenzotrifluoride 651-83-2 (CAS 651-83-2)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
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