(6-Aminoindolin-1-yl)(thiophen-2-yl)methanone CAS 927997-00-0

Description

The occurrence of (6-Aminoindolin-1-yl)(thiophen-2-yl)methanone is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(6-Aminoindolin-1-yl)(thiophen-2-yl)methanone (CAS 927997-00-0), molecular formula C13H12N2OS and molecular weight 244.31 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, (6-Aminoindolin-1-yl)(thiophen-2-yl)methanone is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 244.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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