Fmoc-Met(CF3)-OH CAS 928654-78-8
| CAS No. | 928654-78-8 |
| Molecular Formula | C20H18F3NO4S |
| Molecular Weight | 425.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Fmoc-Met(CF3)-OH (CAS 928654-78-8) is a high-purity analytical reference standard with the molecular formula C20H18F3NO4S and a molecular weight of 425.42 g/mol.
The molecular framework of Fmoc-Met(CF3)-OH (C20H18F3NO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Fmoc-Met(CF3)-OH meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18F3NO4S |
| Molecular Weight | 425.42 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-Amino-6-mercaptopurine-9-(2,3,5-tri-O-acetyl-β-ribofuranosyl)purine (CAS 2946-36-3)
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- 1-(3-Nitrophenyl)-2-(triphenylphosphoranylidene)ethanone (CAS 61748-04-7)
- tert-Butyl 2'-(((trifluoromethyl)sulfonyl)oxy)-5',6'-dihydrospiro[piperidine-4,4'-pyrrolo[1,2-b]pyrazole]-1-carboxylate (CAS 2751664-13-6)
- 2-(Methylsulfonyl)naphthalene (CAS 35330-75-7)
- 4-(Dimethylamino)-2-hydroxy-N,N-dimethylbenzamide (CAS 1243473-12-2)
- N-(2-amino-4-ethoxyphenyl)-2-hydroxypropanamide (CAS 883291-43-8)
- (4-Methyl-2-(1H-pyrrol-1-yl)thiazol-5-yl)(3-(methylthio)-8-azabicyclo[3.2.1]octan-8-yl)methanone (CAS 1705310-13-9)
- N-(2-(2-(1H-Pyrazol-1-yl)thiazol-4-yl)ethyl)-2-ethoxybenzamide (CAS 1448053-21-1)
- 1-(1,1-Dimethylethyl) 1,1-cyclobutanedicarboxylate (CAS 464183-34-4)
- Fmoc-Val-Bt (CAS 1126433-37-1)
- 1-((4-Bromophenyl)sulfonyl)piperidin-4-ol (CAS 937012-61-8)
- 4-(3,5-Dichlorophenyl)butanoic acid (CAS 899350-18-6)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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