2-Chloropyrido[2,3-d]pyrimidin-4(3H)-one CAS 93049-38-8
| CAS No. | 93049-38-8 |
| Molecular Formula | C7H4ClN3O |
| Molecular Weight | 181.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloropyrido[2,3-d]pyrimidin-4(3H)-one.
2-Chloropyrido[2,3-d]pyrimidin-4(3H)-one (CAS 93049-38-8) is a high-purity analytical reference standard with the molecular formula C7H4ClN3O and a molecular weight of 181.58 g/mol.
2-Chloropyrido[2,3-d]pyrimidin-4(3H)-one (C7H4ClN3O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4ClN3O |
| Molecular Weight | 181.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyrido Standards
- 6-Chloropyrido[2,3-b]pyrazin-3(4H)-one (CAS 1350925-21-1)
- 2-Chloropyrido[4,3-d]pyrimidin-5(6H)-one (CAS 1393570-12-1)
- 4-Chloropyrido[2,3-d]pyridazin-5(6H)-one (CAS 1433204-20-6)
- 2-Chloropyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1437435-10-3)
- 3-Chloropyrido[2,3-d]pyridazin-5(6H)-one (CAS 1447949-70-3)
- 2-Chloropyrido[2,3-d]pyridazin-5(6H)-one (CAS 1447958-87-3)
- 5-Chloropyrido[3,4-b]pyrazin-2(1H)-one (CAS 1600511-79-2)
- 8-Chloropyrido[2,3-b]pyrazin-6(5H)-one (CAS 1613289-27-2)
Recommended Standards
- 2-ChlorobenzoylIsocyanate (CAS 4461-34-1)
- 2-Chloropyrido[3,2-d]pyrimidin-4(3H)-one (CAS 2031259-38-6)
- 2-chloro-8H-pyrido[2,3-d]pyrimidin-7-one (CAS 2772659-15-9)
- 3-Chloro-1H-pyrazolo[3,4-b]pyridine-4-carbaldehyde (CAS 2034402-69-0)
- 1-(2,4-Difluorophenyl)-2-(methylthio)propan-1-one (CAS 133825-95-3)
- tert-Butyl 4-(4-fluorobenzyl)-1,4-diazepane-1-carboxylate (CAS 1190967-30-6)
- (1R,2R)-Methyl 2-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate (CAS 267230-27-3)
- 2-Ethyl-4,5-dimethylphenol (CAS 2219-78-5)
- 5-Bromo-6-hydroxynicotinaldehyde (CAS 952183-35-6)
- 3-((6,8-Dibromoquinazolin-4-yl)amino)propanoic acid (CAS 886500-14-7)
- 1-(1-Methylcyclopentyl)ethan-1-one (CAS 13388-93-7)
- 4-(3-Bromobenzyl)thiomorpholine (CAS 414893-81-5)
- N-(4,6-dimethylpyrimidin-2-yl)-1H-benzo[d]imidazol-2-amine (CAS 19206-90-7)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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