4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol hydrochloride CAS 932016-10-9
| CAS No. | 932016-10-9 |
| Molecular Formula | C15H11BrFN3O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol hydrochloride (CAS 932016-10-9), a certified reference material (molecular formula C15H11BrFN3O2HCl, MW 400.63 g/mol) for analytical method development and quality control.
The molecular framework of 4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol hydrochloride (C15H11BrFN3O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11BrFN3O2 HCl |
| Molecular Weight | 400.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 4,9-Bis(5-bromo-2-thienyl)-6,7-bis[4-[(2-ethylhexyl)oxy]phenyl][1,2,5]thiadiazolo[3,4-g]quinoxaline (CAS 1000000-25-8)
- 14-Bromo-1-tetradecyne (CAS 1000014-24-3)
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Recommended Standards
- tert-Butyl 4-hydroxy-1H-indazole-1-carboxylate (CAS 1228874-81-4)
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- 3-Iodo-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one (CAS 142189-88-6)
- Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[3.5]non-2-ene-7-carboxylate (CAS 2864444-56-2)
- Bz-Thr-OMe (CAS 79893-89-3)
- (6-Bromo-2,3-difluorophenyl)trimethylsilane (CAS 473417-24-2)
- Tert-butyl (4-(hydroxymethyl)bicyclo[2.2.1]Heptan-1-yl)carbamate (CAS 1417551-43-9)
- 3-(Thiophen-2-yl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603067-13-6)
- D-Glu3-Tirzepatide (CAS CATO-CPTD788927)
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