2,6-Bis(3-bromo-4-hydroxybenzylidene)cyclohexanone CAS 932749-62-7
| CAS No. | 932749-62-7 |
| Molecular Formula | C20H16Br2O3 |
| Molecular Weight | 464.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,6-Bis(3-bromo-4-hydroxybenzylidene)cyclohexanone (CAS 932749-62-7), molecular formula C20H16Br2O3 and molecular weight 464.15 g/mol, is a CATO reference standard with documented purity and traceability.
2,6-Bis(3-bromo-4-hydroxybenzylidene)cyclohexanone (C20H16Br2O3) contains a steroid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16Br2O3 |
| Molecular Weight | 464.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
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Recommended Standards
- Methyl (3E)-2-[(2,4-dichlorophenyl)formamido]-3-{[(2,6-dichlorophenyl)methoxy]imino}propanoate (CAS 318517-64-5)
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- 1H,1H,2H,2H-Perfluoro-1-decanol (CAS 678-39-7)
- Bis(1,1,1,3,3,3-hexafluoropropan-2-yl) terephthalate (CAS 159852-53-6)
- 3-[(2-methoxyethyl)amino]propanoic acid (CAS 1040073-81-1)
- 3-((2-(Benzyloxy)ethyl)(phenyl)amino)propanenitrile (CAS 25047-90-9)
- ThioFluor 623 (CAS 1004324-99-5)
- 1-(Prop-2-yn-1-yl)indolin-2-one (CAS 37994-11-9)
- bis(1-[2-(4-sulfamoylphenyl)ethyl]guanidine), sulfuric acid (CAS 1803593-22-7)
- 2-(Aminomethyl)-4-(cyclohexylmethyl)phenol (CAS 1243363-81-6)
- Propan-2-yl 5-bromo-2-fluorobenzoate (CAS 1369403-80-4)
- Ruxolitinib Impurity 73 (CAS CATO-C4X-205873)
- 1-(bromomethyl)-3-methylenecyclobutane (CAS 10555-46-1)
- Characteristic MSH-Tetrapeptide (CAS 4289-02-5)
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