[1-(2-chlorophenyl)cyclohexyl]methanamine CAS 933727-15-2

Description

The occurrence of [1-(2-chlorophenyl)cyclohexyl]methanamine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

[1-(2-chlorophenyl)cyclohexyl]methanamine (CAS 933727-15-2) is a high-purity analytical reference standard with the molecular formula C13H18ClN and a molecular weight of 223.74 g/mol.

The molecular framework of [1-(2-chlorophenyl)cyclohexyl]methanamine (C13H18ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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