2-(6-Fluoro-1-methyl-2-oxoindolin-3-yl)acetic acid CAS 933752-43-3
| CAS No. | 933752-43-3 |
| Molecular Formula | C11H10FNO3 |
| Molecular Weight | 223.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(6-Fluoro-1-methyl-2-oxoindolin-3-yl)acetic acid (C11H10FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(6-Fluoro-1-methyl-2-oxoindolin-3-yl)acetic acid (CAS 933752-43-3), molecular formula C11H10FNO3 and molecular weight 223.20 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10FNO3 |
| Molecular Weight | 223.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
- 1,2-Benzenedicarboxylic Acid Mono(2-hydroxypropyl) Ester (CAS 57340-51-9)
- 2-(difluoromethoxy)benzene-1-sulfonamide (CAS 77798-20-0)
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- 2-[(2-Fluorophenyl)carbamoyl]cyclopropane-1-carboxylic acid (CAS 866150-96-1)
- (R)-N,1-Dimethyl-5-oxopyrrolidine-2-carboxamide (CAS 182803-79-8)
- (4-(Mercaptomethyl)phenyl)boronic acid (CAS 847801-60-9)
- 1-Isopropyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid (CAS 436811-11-9)
- 4-Iodo-2-nitrobenzaldehyde (CAS 60184-79-4)
- 4-Chloro-N-cyclohexylbenzenesulfonamide (CAS 7454-53-7)
- 2-Oxo-1,2-dihydropyridine-3-carboximidamide (CAS 885953-80-0)
- 4-(m-Tolyl)tetrahydro-2H-pyran-4-amine (CAS 1094686-38-0)
- 4-oxo Tolimidone (CAS 66047-04-9)
- 4-Methanesulfonyl-2-nitrophenylboronic acid (CAS 2377609-89-5)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
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