5,6-difluoro-3,4-dihydroquinazolin-4-one CAS 933823-89-3
| CAS No. | 933823-89-3 |
| Molecular Formula | C8H12F2N2O |
| Molecular Weight | 190.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5,6-difluoro-3,4-dihydroquinazolin-4-one (CAS 933823-89-3) is a high-purity analytical reference standard with the molecular formula C8H12F2N2O and a molecular weight of 190.19 g/mol.
The molecular framework of 5,6-difluoro-3,4-dihydroquinazolin-4-one (C8H12F2N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12F2N2O |
| Molecular Weight | 190.19 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related difluoro Standards
- 5,6-difluoro-1H-1,3-benzodiazole-2-carbaldehyde (CAS 1263379-05-0)
- 6,7-difluoro-1,2-dihydroquinoxalin-2-one (CAS 137690-08-5)
- 6,7-difluoro-1,4-dihydrocinnolin-4-one (CAS 1934937-35-5)
- 2,2-difluoro-7-methyl-benzofuran-3-one (CAS 2644051-76-1)
- 2,5-difluoro-4-(3-hydroxyprop-1-ynyl)phenol (CAS 2283380-33-4)
- 2,6-Difluoro-1,1'-biphenyl (CAS 2285-29-2)
- 3-(1,1-Difluoro-2,2-dimethylpropyl)isoxazol-5-amine (CAS 2770403-97-7)
- 3,3'-Difluoro-1,1'-biphenyl (CAS 396-64-5)
Recommended Standards
- 4-Methylphenyl fluorosulfonate (CAS 660-34-4)
- CHO-C-PEG2-C-CHO (CAS 92351-72-9)
- 4-Fluorophenyl methanesulfonate (CAS 72358-72-6)
- Diethyl 2-(hydroxymethyl)malonate (CAS 23904-38-3)
- Methyl 2-methyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (CAS 1638761-10-0)
- 3-Methoxypyrrolidin-1-amine (CAS 887591-13-1)
- (4-Hydroxyphenyl)(pyridin-3-yl)methanone (CAS 35926-15-9)
- Sodium perfluorononyloxybenzenesulfonate (CAS 77061-68-8)
- 9,10-Dihydroanthracene-9,10-diol (CAS 58343-58-1)
- N-(4-phenoxyphenyl)-2-(3-(trifluoromethyl)phenyl)acetamide (CAS 338400-84-3)
- 2-(2-(Heptan-2-ylamino)ethoxy)ethan-1-ol (CAS 1042523-06-7)
- 2-Fluoro-4-mercaptobenzonitrile (CAS 101187-91-1)
- Methyl 2,4-dibromopyrimidine-5-carboxylate (CAS 1935357-44-0)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com