N-Ethyl-5-iodo-6-methyl-2-(methylthio)pyrimidin-4-amine CAS 934493-77-3
| CAS No. | 934493-77-3 |
| Molecular Formula | C8H12IN3S |
| Molecular Weight | 309.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-Ethyl-5-iodo-6-methyl-2-(methylthio)pyrimidin-4-amine.
N-Ethyl-5-iodo-6-methyl-2-(methylthio)pyrimidin-4-amine (CAS 934493-77-3) is a high-purity analytical reference standard with the molecular formula C8H12IN3S and a molecular weight of 309.17 g/mol.
N-Ethyl-5-iodo-6-methyl-2-(methylthio)pyrimidin-4-amine (C8H12IN3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12IN3S |
| Molecular Weight | 309.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
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