Olodaterol impurity 24 CAS 936490-85-6
| CAS No. | 936490-85-6 |
| Molecular Formula | C20H24N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 408.88 g/mol gives Olodaterol impurity 24 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Olodaterol impurity 24 (CAS 936490-85-6), a pharmacopoeial impurity reference standard (molecular formula C20H24N2O5HCl, MW 408.88 g/mol) used for the identification and quantification of trace impurities in APIs.
Olodaterol impurity 24 (C20H24N2O5HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O5 HCl |
| Molecular Weight | 408.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Olodaterol Standards
- Olodaterol Impurity 1 (CAS 78-09-1)
- Olodaterol (CAS 868049-49-4)
- (S)-Olodaterol (CAS 868049-50-7)
- (S)-Olodaterol hydrochloride (CAS 868049-50-7(free base))
- Olodaterol Hydrochloride (CAS 869477-96-3)
- Olodaterol Impurity N6 (CAS 869478-10-4)
- (R)-Olodaterol Benzyl Ether (CAS 869478-13-7)
- (R)-Olodaterol Benzyl Ether HCl (CAS 869478-13-7(Free Base))
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