4,7-Dichloro-8-fluoroquinoline-3-carbonitrile CAS 936498-03-2
| CAS No. | 936498-03-2 |
| Molecular Formula | C10H3Cl2FN2 |
| Molecular Weight | 241.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,7-Dichloro-8-fluoroquinoline-3-carbonitrile (C10H3Cl2FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 4,7-Dichloro-8-fluoroquinoline-3-carbonitrile (CAS 936498-03-2), a certified reference material (molecular formula C10H3Cl2FN2, MW 241.05 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,7-Dichloro-8-fluoroquinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H3Cl2FN2 |
| Molecular Weight | 241.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 4,8-Dichloro-6-fluoroquinoline-3-carbonitrile (CAS 1016496-67-5)
- 4,5-Dichloro-8-fluoroquinoline-3-carbonitrile (CAS 1017051-94-3)
- 2,4-Dichloro-8-fluoroquinoline-3-carbonitrile (CAS 1446408-71-4)
- 2,4-Dichloro-6-fluoroquinoline-3-carbonitrile (CAS 881313-89-9)
- 4,6-Dichloro-8-fluoroquinoline-3-carbonitrile (CAS 936498-06-5)
- 4,7-Dichloro-6-fluoroquinoline-3-carbonitrile (CAS 886362-74-9)
- 2,4-dichloro-1-phenyl-1H-imidazole-5-carbaldehyde (CAS 1181458-32-1)
- 4,5-Dichloro-2-phenyl-3(2H)-pyridazinone (CAS 1698-53-9)
Recommended Standards
- 4-Iodo-3-methoxyisothiazole (CAS 60666-89-9)
- 5-Iodo-2-methoxythiazole (CAS 2137792-51-7)
- 3-(Benzoylamino)phenylboronic acid (CAS 252663-49-3)
- 3-Bromo-6-fluoroquinolin-4-amine (CAS 1065088-21-2)
- Iprovalicarb (CAS 140923-17-7)
- 3-bromo-1-(oxan-2-yl)-1H-pyrazolo[3,4-b]pyridine (CAS 1416713-33-1)
- Methyl 2-formyl-6-(pyridin-3-ylmethoxy)nicotinate (CAS 1774903-61-5)
- 3-Methoxymorphinan Hydrochloride (CAS 36397-14-5)
- Di-t-butyl(2-butenyl)phosphine (40% in xylene), 98% m-Crophos (CAS 1620882-90-7)
- (1R,4R)-{4-[(2-Amino-acetyl)-ethyl-amino]-cyclohexyl}-carbamic acid tert-butylester (CAS 1353992-89-8)
- N1-Cycloheptyl-N2-(3-(4-(dimethylamino)phenyl)propyl)oxalamide (CAS 953987-56-9)
- 4-(Propan-2-ylidene)tetrahydro-2H-pyran (CAS 26170-24-1)
- 4-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-one (CAS 1083090-91-8)
- Tirzepatide Impurity 61 (CAS CATO-C4X-324061)
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