6-cyclopropyl-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid CAS 937598-64-6
| CAS No. | 937598-64-6 |
| Molecular Formula | C17H14FN3O2 |
| Molecular Weight | 311.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6-cyclopropyl-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 937598-64-6), molecular formula C17H14FN3O2 and molecular weight 311.31 g/mol, is a CATO reference standard with documented purity and traceability.
6-cyclopropyl-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (C17H14FN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H14FN3O2 |
| Molecular Weight | 311.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related cyclopropyl Standards
- methyl 6-cyclopropyl-1-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011396-81-8)
- 3-Cyclopropyl-1-(4-fluorophenyl)-6-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-49-1)
- 3-Cyclopropyl-1-(2-fluorophenyl)-6-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018164-82-3)
- 2-(3-Cyclopropyl-4-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937606-50-3)
- 1-(4-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid (CAS 1338652-75-7)
- 1-[5-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]-5-methyl-1H-pyrazole-4-carboxylic acid (CAS 1351398-62-3)
- Methyl 2-cyclopropyl-5-(3,5-dimethylisoxazol-4-yl)-1H-benzo[d]imidazole-7-carboxylate (CAS 1637771-11-9)
- 4-Cyclopropyl-5-(furan-2-yl)-2-(3-methoxybenzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 1797847-21-2)
Recommended Standards
- 5-Amino-1-benzyl-N-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899749-80-5)
- 7-Acetamido-1-desmethyl Flunitrazepam (CAS 74723-07-2)
- 5-Amino-1-benzyl-N-(2-fluorophenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899749-78-1)
- Benzoin Hemisuccinate (CAS 24248-42-8)
- Spiro[2.5]octan-4-amine (CAS 78293-96-6)
- Tert-Butyl (5-methylpyridine-3-yl)carbamate (CAS 631910-23-1)
- 2-Amino-3-(3,5-difluoro-4-hydroxyphenyl)propanoic acid (CAS 369-96-0)
- N-((1-(2,2-Difluoroethyl)-5-methyl-1H-pyrazol-4-yl)methyl)-3-methoxy-1-methyl-1H-pyrazol-4-amine hydrochloride (CAS 1856092-47-1)
- 1-Benzyl-2-oxo-1,2-dihydropyridine-3-carbohydrazide (CAS 242472-15-7)
- N-(4-Bromophenyl)-3-oxobutanamide (CAS 38418-24-5)
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- 3-[(3-Nitrophenoxy)methyl]pyrrolidinehydrochloride (CAS 1219982-35-0)
- N-Hydroxy-5-methyl-1,2,4-oxadiazole-3-carboximidamide (CAS 162969-65-5)
- T-Peptide (CAS 2022956-62-1)
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