3-(2-Bromo-4-fluorophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one CAS 937601-60-0
| CAS No. | 937601-60-0 |
| Molecular Formula | C14H8BrFN2OS |
| Molecular Weight | 351.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 351.19 g/mol gives 3-(2-Bromo-4-fluorophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(2-Bromo-4-fluorophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 937601-60-0), molecular formula C14H8BrFN2OS and molecular weight 351.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(2-Bromo-4-fluorophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (C14H8BrFN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(2-Bromo-4-fluorophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8BrFN2OS |
| Molecular Weight | 351.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 4-(4-Carboxybenzamido)benzoic acid (CAS 56419-89-7)
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- N-butyl-2-hydroxy-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide (CAS 886913-14-0)
- 2-(Azepan-1-ylsulfonyl)ethan-1-amine (CAS 926211-37-2)
- 4-(4-(5-Fluoropyrimidin-2-yl)piperazin-1-yl)aniline (CAS 1921374-52-8)
- Ethyl 2-oxobutanoate (CAS 15933-07-0)
- 4-Chloro-N-(5-chloro-2-formylphenyl)benzenesulfonamide (CAS 922711-94-2)
- 2-Amino-5-[(dimethylamino)methyl]pyridine (CAS 1197404-30-0)
- 1-Cyclopropyl-2-((3-methylbenzyl)thio)ethan-1-one (CAS 1343852-13-0)
- PACAP-Related Peptide (PRP), rat (CAS 132769-35-8)
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