3-Chloro-2-(p-tolyloxy)aniline CAS 937604-53-0
| CAS No. | 937604-53-0 |
| Molecular Formula | C13H12ClNO |
| Molecular Weight | 233.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 233.69 g/mol gives 3-Chloro-2-(p-tolyloxy)aniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Chloro-2-(p-tolyloxy)aniline (CAS 937604-53-0), a certified reference material (molecular formula C13H12ClNO, MW 233.69 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-2-(p-tolyloxy)aniline (C13H12ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12ClNO |
| Molecular Weight | 233.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 3-Chloro-2-(m-tolyloxy)aniline (CAS 937604-51-8)
- 3-Chloro-4-(2-methylphenoxy)aniline (CAS 56966-57-5)
- 3-Chloro-2-(2-methylphenoxy)aniline (CAS 946714-66-5)
- 3-Chloro-4-(3-methylphenoxy)aniline (CAS 56966-56-4)
- 2-Methyl-N-((1-methyl-1h-pyrazol-4-yl)methyl)pyridin-3-amine (CAS 1509876-45-2)
- Angiogenin Fragment (108-122) (CAS 112173-49-6)
- 2,4,6-Tribromopyrimidine 36847-11-7 C4HBr3N2 Y8883 (CAS 36847-11-7)
- (2,5-Difluorophenyl)(3-methanesulfonylphenyl)methanone (CAS 1096958-65-4)
- 7-Bromo-4-chloro-2-(chloromethyl)quinazoline (CAS 573681-19-3)
- 6-Chloro-1-(2-methoxyphenyl)hexan-1-one (CAS 501083-60-9)
- 4,6-Dichloro-2-(methylsulfonyl)-5-nitropyrimidine (CAS 127726-62-9)
- 4-Aminophenylphosphorylcholine (CAS 102185-28-4)
- 5-[2-(3,5-Dimethyl-pyrazol-1-yl)-ethyl]-[1,3,4]-thiadiazol-2-ylamine (CAS 957484-31-0)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
Why CATO?
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