[3-methyl-6-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid CAS 937605-80-6
| CAS No. | 937605-80-6 |
| Molecular Formula | C16H12F3N3O2 |
| Molecular Weight | 335.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies [3-methyl-6-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937605-80-6), a certified reference material (molecular formula C16H12F3N3O2, MW 335.28 g/mol) for analytical method development and quality control.
Structurally, [3-methyl-6-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (C16H12F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 335.28 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures [3-methyl-6-phenyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12F3N3O2 |
| Molecular Weight | 335.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- 2-Methoxy-4-(3-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-5-yl)phenol (CAS 1416345-46-4)
- 1-((1-(3-(Trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)oxy)propan-2-one (CAS 34580-66-0)
- NHI 2 (CAS 1269802-97-2)
- 2-((Tert-butoxycarbonyl)amino)-2-(4-(trifluoromethoxy)phenyl)acetic acid (CAS 301196-85-0)
- 2-((Benzyloxy)carbonyl)-8-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]decane-4-carboxylic acid (CAS 1251003-34-5)
- Ethyl 2-ethyl-5-methyl-1-oxaspiro[2.5]octane-2-carboxylate (CAS 855842-96-5)
- (2R,4S)-2-(1,1-Dimethylethyl)-4-methyl-1,3-oxathiolan-5-one (CAS 476371-85-4)
- tert-butyl 3-(1-methyltriazol-4-yl)propanoate (CAS 2010114-80-2)
- 3-Methoxy-2-(oxiran-2-ylmethoxy)benzonitrile (CAS 35198-39-1)
- 3-Phenyl-1-(p-tolyl)-1h-pyrazol-5-amine (CAS 77746-54-4)
- 3,4-Dibromodiphenyl Ether (CAS 189084-59-1)
- 4-Chloro-3-ethylpyridine (CAS 860411-22-9)
- 2-(1,3-Benzodioxol-5-yl)quinoline-4-carbohydrazide (CAS 524932-89-6)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
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