2-(3-Cyclopropyl-6-(furan-2-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid CAS 937606-04-7
| CAS No. | 937606-04-7 |
| Molecular Formula | C16H12F3N3O3 |
| Molecular Weight | 351.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3-Cyclopropyl-6-(furan-2-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid.
2-(3-Cyclopropyl-6-(furan-2-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937606-04-7) is a high-purity analytical reference standard with the molecular formula C16H12F3N3O3 and a molecular weight of 351.28 g/mol.
2-(3-Cyclopropyl-6-(furan-2-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (C16H12F3N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12F3N3O3 |
| Molecular Weight | 351.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cyclopropyl Standards
- 1391054-38-8 2-[[N-Cyclopropyl-(3-fluoro-4-methoxyphenyl)amino]methylene]-propanedioic Acid 1,3-Diethyl Ester (CAS 1391054-38-8)
- 3-Cyclopropyl-6-isopropyl-1-(4-methoxyphenyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018164-91-4)
- 2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS 1340154-82-6)
- 3-(Cyclopropyl[(9h-fluoren-9-ylmethoxy)carbonyl]amino)propanoic acid (CAS 1343275-93-3)
- 3-Cyclopropyl-3-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS 683217-51-8)
- 3-Cyclopropyl-1-((2,4,5-trichlorophenyl)sulfonyl)-1H-pyrazole (CAS 955962-40-0)
- Cyclopropyl 3,4,5-trifluorophenyl ketone (CAS 898790-38-0)
- N-Cyclopropyl-2-(2-((2-(4-fluorophenyl)-2-oxoethyl)thio)thiazol-4-yl)acetamide (CAS 1021035-03-9)
Recommended Standards
- 2-(1-(4-Bromophenyl)-3,3-bis(methylthio)allylidene)malononitrile (CAS 89482-72-4)
- N-(2,5-dioxo-5,6,7,8-tetrahydro-2H-chromen-3-yl)-3-(trifluoromethyl)benzamide (CAS 338405-02-0)
- 1,1-Dimethyl-3-(5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridin-3-yl)urea (CAS 303995-23-5)
- N-(3-Bromophenyl)-4-(methylthio)benzo[d]thiazol-2-amine (CAS 890961-65-6)
- N-(3-aminopropyl)-3-fluoro-N-methylaniline (CAS 1018650-35-5)
- 3-(1-Methyl-6-oxo-1,6-dihydropyridazin-3-yl)-N-(thiophen-2-ylmethyl)propanamide (CAS 1797160-47-4)
- Dibenzyl azetidine-1,2-dicarboxylate (CAS 912335-89-8)
- 6-Bromo-2-(chloromethyl)imidazo[1,2-a]pyridine hydrochloride (CAS 1172561-55-5)
- 2-(Benzylamino)-1-(piperidin-1-yl)ethan-1-one (CAS 100875-44-3)
- 4-(Difluoromethyl)-6-methoxy-3-nitropyridin-2-amine (CAS 1806796-97-3)
- tert-Butyl 3-{[(4-chlorophenyl)methyl]amino}propanoate (CAS 1221341-35-0)
- (2-((tert-Butoxycarbonyl)(methyl)amino)pyrimidin-5-yl)boronic acid (CAS 1033744-52-3)
- Methyl 3-(Benzyloxy)-2,6-difluorobenzoate (CAS 2635937-50-5)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com