3-Methyl-1-(2-methylpropyl)-2,4-dioxo-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-6-carboxylic acid CAS 937624-04-9

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 3-Methyl-1-(2-methylpropyl)-2,4-dioxo-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-6-carboxylic acid (CAS 937624-04-9), a certified reference material (molecular formula C13H15N3O4, MW 277.28 g/mol) for analytical method development and quality control.

The molecular framework of 3-Methyl-1-(2-methylpropyl)-2,4-dioxo-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-6-carboxylic acid (C13H15N3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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