4-[(2-amino-1,3-thiazol-5-yl)methyl]-3-(trifluoromethyl)benzonitrile CAS 937629-00-0
| CAS No. | 937629-00-0 |
| Molecular Formula | C12H8F3N3S |
| Molecular Weight | 283.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-[(2-amino-1,3-thiazol-5-yl)methyl]-3-(trifluoromethyl)benzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-[(2-amino-1,3-thiazol-5-yl)methyl]-3-(trifluoromethyl)benzonitrile (CAS 937629-00-0), molecular formula C12H8F3N3S and molecular weight 283.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(2-amino-1,3-thiazol-5-yl)methyl]-3-(trifluoromethyl)benzonitrile (C12H8F3N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8F3N3S |
| Molecular Weight | 283.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related amino Standards
- 2-Amino-9-((1R,2R,3R,4R)-2-fluoro-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-1H-purin-6(9H)-one(relative) (CAS 110289-24-2)
- 2-Amino-9-((1S,2R,3R,4S)-2-fluoro-4-hydroxy-3-(hydroxymethyl)cyclopentyl)-1H-purin-6(9H)-one (CAS 131043-40-8)
- 2-Amino-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidin-4(1H)-one (CAS 5975-05-3)
- 2-Amino-4,6-bis(4-fluorophenyl)pyrimidine (CAS 512190-82-8)
- 2-Amino-5-methoxybenzene-1,4-disulfonic acid (CAS 27327-48-6)
- 2-Amino-7-hydroxy-3-(2-methoxyphenyl)-4H-chromen-4-one (CAS 929429-04-9)
- Ethyl 3-Amino-5-(2,4-difluorophenyl)thiophene-2-carboxylate (CAS 1096972-46-1)
- Ethyl5-amino-1-(quinoxalin-2-yl)-1h-pyrazole-4-carboxylate (CAS 1190002-59-5)
Recommended Standards
- 2-Methyl-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 434294-44-7)
- 5-[4-(Trifluoromethoxy)phenyl]-5H-thieno[2,3-c]pyrrole (CAS 338780-82-8)
- 2-[(2,4-difluorophenyl)carbamoyl]cyclohexane-1-carboxylic acid (CAS 392703-95-6)
- 6-(p-Tolyl)-2-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazole (CAS 674283-92-2)
- 1-(2,5-dichlorophenyl)-N-(4-fluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 338398-37-1)
- 1-Ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid (CAS 405112-23-4)
- 1,2,3,5-Tetrahydroimidazo[1,2-a]pyrimidine (CAS 651043-44-6)
- (R)-1-(3-(trifluoromethyl)phenyl)pentan-1-amine (CAS 1213482-69-9)
- n-(Propan-2-yl)oxan-3-amine (CAS 1343450-12-3)
- 5-(6-Chloropyridazin-3-yl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (CAS 1094223-56-9)
- 1-(3-CHloro-4-methyl-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester (CAS 345367-42-2)
- 7-Benzyl-2-methyl-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one (CAS 1392817-32-1)
- (S)-1-(1-Isocyanatoethyl)-4-methoxybenzene (CAS 745783-83-9)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com