4-Chloro-3-thiophenesulfonyl chloride CAS 937636-93-6

Purity 97%+In StockPharmaceutical Standards
CAS No.937636-93-6
Molecular FormulaC4H2Cl2O2S2
Molecular Weight217.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-3-thiophenesulfonyl chloride CAS 937636-93-6 chemical structure

Description

The occurrence of 4-Chloro-3-thiophenesulfonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Chloro-3-thiophenesulfonyl chloride (CAS 937636-93-6), molecular formula C4H2Cl2O2S2 and molecular weight 217.09 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Chloro-3-thiophenesulfonyl chloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 217.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Chloro-3-thiophenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H2Cl2O2S2
Molecular Weight217.09 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Sulfur Atoms2

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