2-[2-(2-chlorophenyl)-1,3-thiazol-4-yl]ethan-1-amine CAS 938377-76-5
| CAS No. | 938377-76-5 |
| Molecular Formula | C11H11ClN2S |
| Molecular Weight | 238.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 238.74 g/mol gives 2-[2-(2-chlorophenyl)-1,3-thiazol-4-yl]ethan-1-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-[2-(2-chlorophenyl)-1,3-thiazol-4-yl]ethan-1-amine (CAS 938377-76-5), molecular formula C11H11ClN2S and molecular weight 238.74 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[2-(2-chlorophenyl)-1,3-thiazol-4-yl]ethan-1-amine (C11H11ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11ClN2S |
| Molecular Weight | 238.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related chlorophenyl Standards
- {[2-(2-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]methyl}amine (CAS 1082119-61-6)
- 5-[(3-chlorophenyl)methyl]-4-methyl-1,3-thiazol-2-amine (CAS 1155998-38-1)
- 1-(2-(3-Chlorophenyl)thiazol-4-yl)-N-methylmethanamine (CAS 864068-99-5)
- 2-(2-(4-Chlorophenyl)thiazol-4-yl)ethan-1-amine (CAS 26858-31-1)
- 2-(4-(4-Chlorophenyl)thiazol-2-yl)ethan-1-amine (CAS 641993-24-0)
- 4-(4-Chlorophenyl)-5-ethyl-1,3-thiazol-2-amine (CAS 313533-99-2)
- 4-[(4-Chlorophenyl)thio]-3,5-dimethyl-1H-pyrazole (CAS 301858-86-6)
- 5-[(2-chlorophenyl)methyl]-4-methyl-1,3-thiazol-2-amine (CAS 446858-94-2)
Recommended Standards
- 3-Chloro-N-[(4-methyl-1,3-thiazol-5-yl)methyl]aniline (CAS 953070-62-7)
- 4-(Chloromethyl)-N-(4-methylphenyl)-1,3-thiazol-2-amine hydrochloride (CAS 33188-18-0)
- (2-(4-Chlorobenzyl)thiazol-4-yl)methanamine (CAS 938119-51-8)
- 4-(3-Chloro-4-methylphenyl)-5-methylthiazol-2-amine (CAS 175278-40-7)
- Ethyl 5-(3-oxocyclohexyl)thiophene-2-carboxylate (CAS 909421-70-1)
- 4-[5-(2,4-Dichlorophenyl)-1-(2-nitrobenzenesulfonyl)-1H-pyrazol-3-yl]piperidine hydrochloride (CAS 1052553-33-9)
- 2-(4-Chlorophenyl)-2-(methylamino)acetonitrile (CAS 199277-95-7)
- [4-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methyl-butanoyl]amino]-5-ureido-pentanoyl]amino]phenyl]methyl N-[(1S)-1-[[(1S)-1-[[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl]amino]-1-methoxy-2-methyl-3-oxo-propyl]pyrrolidin-1-yl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxo-butyl]-methyl-carbamoyl]-2-methyl-propyl]carbamoyl]-2-methyl-propyl]-N-methyl-carbamate (CAS 1350456-56-2)
- 1,4-Dibromo-2-methyl-5-nitrobenzene (CAS 219310-40-4)
- 3-Methyl-4-nitro-pyrazole-1-carboxylic acid tert-butyl ester (CAS 847139-22-4)
- Ethyl 4-(2,3-dimethoxyphenyl)-4-oxobutanoate (CAS 898758-05-9)
- Tert-butyl 2-amino-9-hydroxy-6-azaspiro[3.5]Nonane-6-carboxylate (CAS 2387596-08-7)
- [(S)-1-(2-Amino-ethyl)-piperidin-3-yl]-isopropyl-carbamic acid tert-butyl ester (CAS 1354002-97-3)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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