Phenylephrine Impurity 14 CAS 939-38-8
| CAS No. | 939-38-8 |
| Molecular Formula | C9H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 203.67 g/mol gives Phenylephrine Impurity 14 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Phenylephrine Impurity 14 (CAS 939-38-8) is a certified pharmaceutical impurity reference standard with the molecular formula C9H13NO2HCl and a molecular weight of 203.67 g/mol.
Phenylephrine Impurity 14 (C9H13NO2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Phenylephrine Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H13NO2 HCl |
| Molecular Weight | 203.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Phenylephrine Standards
- Phenylephrine Impurity 58 (CAS 1007885-60-0)
- Phenylephrine Impurity 100 (CAS 1026633-55-5)
- Phenylephrine Related Compound G (CAS 1094089-46-9)
- Phenylephrine EP Impurity D Racemate (CAS 1159977-09-9)
- Phenylephrine Impurity 18 (Mixture of Diastereomers) (CAS 1217525-08-0)
- Phenylephrine-d3 HCl (Methyl-d3) (CAS 1217858-50-8)
- Phenylephrine-3-O-Sulfate (CAS 1242184-39-9)
- Phenylephrine 2-O-β-glucuronide, >98% (CAS 1260611-56-0)
Recommended Standards
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- Crisaborole Impurity 49 (CAS CATO-C4X-202149)
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- (3-(Bromomethyl)-4-chlorophenyl)pentafluoro-lambda6-sulfane (CAS 1431329-74-6)
- N-methyl-1-(oxazol-2-yl)cyclopropan-1-amine (CAS 2315377-61-6)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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