Methyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate CAS 939979-80-3
| CAS No. | 939979-80-3 |
| Molecular Formula | C10H8N2O4 |
| Molecular Weight | 220.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate.
CATO supplies Methyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate (CAS 939979-80-3), a certified reference material (molecular formula C10H8N2O4, MW 220.18 g/mol) for analytical method development and quality control.
Methyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate (C10H8N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O4 |
| Molecular Weight | 220.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 1-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylic acid (CAS 1038385-70-4)
- 2,4-Dioxo-1,2,3,4-tetrahydroquinazolin-6-yl acetate (CAS 119278-36-3)
- (S)-2-(1,3-Dioxo-1,3-dihydro-2h-pyrrolo[3,4-c]pyridin-2-yl)propanoic acid (CAS 1212191-11-1)
- 3-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)propanoic acid (CAS 131570-34-8)
- 2-(5,7-Dioxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)propanoic acid (CAS 131615-98-0)
- Methyl 1,4-dioxo-1,2,3,4-tetrahydrophthalazine-5-carboxylate (CAS 1707667-86-4)
- 4-(3,5-Dioxo-1,2,4-triazolidin-4-yl)benzamide (CAS 172510-63-3)
- Methyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate (CAS 174074-88-5)
Recommended Standards
- Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate (CAS 354793-04-7)
- Methyl 2-hydroxy-4-oxo-4h-pyrido[1,2-a]pyrimidine-3-carboxylate (CAS 224313-74-0)
- Methyl 2,2-bis((methoxycarbonyl)amino)acetate (CAS 60794-51-6)
- Methyl 5-(2-formyl-1H-pyrrol-1-yl)-1H-1,2,4-triazole-3-carboxylate (CAS 554402-33-4)
- 2-Fluoro-5-methyl-N-(3-methylbutan-2-yl)aniline (CAS 1039957-75-9)
- 3-((3-Hydroxypropyl)amino)propanamide oxalate (CAS 1201633-44-4)
- (1R,2S,5R)-5-Methyl-2-(2-phenylpropan-2-yl)cyclohexyl 2-chloroacetate (CAS 71804-27-8)
- m-Tolyl Chloroformate (CAS 29430-39-5)
- 1,1-Diphenylpropane-1,2-diol (CAS 52183-00-3)
- (Carboxymethyloximino)spiperone Hemihydrate (CAS 355012-90-7)
- 2-chloro-N,N-dimethylquinazolin-4-amine (CAS 35691-16-8)
- 2-Chloro-N-(4-(morpholinomethyl)benzyl)propanamide (CAS 1097816-84-6)
- 2-(3,5-Dibromo-1H-1,2,4-triazol-1-yl)acetamide (CAS 919266-86-7)
- C-Peptide (human) (CAS 33017-11-7)
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