4-Chloro-3-methanesulfonamidobenzoic acid CAS 94101-69-6
| CAS No. | 94101-69-6 |
| Molecular Formula | C8H8ClNO4S |
| Molecular Weight | 249.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-3-methanesulfonamidobenzoic acid.
4-Chloro-3-methanesulfonamidobenzoic acid (CAS 94101-69-6) is a high-purity analytical reference standard with the molecular formula C8H8ClNO4S and a molecular weight of 249.67 g/mol.
4-Chloro-3-methanesulfonamidobenzoic acid (C8H8ClNO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-3-methanesulfonamidobenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO4S |
| Molecular Weight | 249.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4,5-dimethyl-2-nitrobenzenesulfonyl chloride (CAS 838840-90-7)
- 4-Chloro-6-ethoxy-2-(methylthio)-5-nitropyrimidine (CAS 56032-34-9)
- 4-(2-Amino-2-oxoethoxy)benzenesulfonyl chloride (CAS 69986-21-6)
- 4-Chloro-N-(4-fluorophenyl)benzamide (CAS 5021-59-0)
- Etifenin CRS (CAS 63245-28-3)
- DMAC-SPP (CAS 663599-10-8)
- Disodium Bilirubinate (CAS 93891-87-3)
- N-Nitroso-Voglibose (CAS CATO-C4X-178020)
- 4-Chloro-N-[4-(2-dimethylamino-5-trifluoromethyl-pyridin-3-yl)-phenyl]-benzamide (CAS 1311280-15-5)
- 4-((2-Fluorophenyl)sulfonyl)piperazin-2-one (CAS 1090525-98-6)
- Amikacin EP Impurity F (CAS 197909-67-4)
- 2-(6-Methoxybenzo[d]thiazol-2-yl)acetonitrile (CAS 64513-30-0)
- 3-Benzyl-7-piperazin-1-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 941867-95-4)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
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