2-[2-Amino-4-(Trifluoromethyl)Phenyl]-3-(2,4-Dichlorophenyl)Acrylic Acid CAS 94133-64-9
| CAS No. | 94133-64-9 |
| Molecular Formula | C16H10Cl2F3NO2 |
| Molecular Weight | 376.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[2-Amino-4-(Trifluoromethyl)Phenyl]-3-(2,4-Dichlorophenyl)Acrylic Acid.
2-[2-Amino-4-(Trifluoromethyl)Phenyl]-3-(2,4-Dichlorophenyl)Acrylic Acid (CAS 94133-64-9), molecular formula C16H10Cl2F3NO2 and molecular weight 376.16 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-[2-Amino-4-(Trifluoromethyl)Phenyl]-3-(2,4-Dichlorophenyl)Acrylic Acid (C16H10Cl2F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 376.16 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[2-Amino-4-(Trifluoromethyl)Phenyl]-3-(2,4-Dichlorophenyl)Acrylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10Cl2F3NO2 |
| Molecular Weight | 376.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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