1-(1-Ethyl-1H-indol-3-yl)-3-(4-fluorobenzyl)urea CAS 941951-38-8
| CAS No. | 941951-38-8 |
| Molecular Formula | C18H18FN3O |
| Molecular Weight | 311.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(1-Ethyl-1H-indol-3-yl)-3-(4-fluorobenzyl)urea (CAS 941951-38-8) is a high-purity analytical reference standard with the molecular formula C18H18FN3O and a molecular weight of 311.35 g/mol.
The molecular framework of 1-(1-Ethyl-1H-indol-3-yl)-3-(4-fluorobenzyl)urea (C18H18FN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(1-Ethyl-1H-indol-3-yl)-3-(4-fluorobenzyl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18FN3O |
| Molecular Weight | 311.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
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