tert-butyl-[rel-(1R,2R,4S)-2-fluoro-4-(iodomethyl)cyclopentoxy]-dimethyl-silane CAS 942143-86-4
| CAS No. | 942143-86-4 |
| Molecular Formula | C12H24FIOSi |
| Molecular Weight | 358.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies tert-butyl-[rel-(1R,2R,4S)-2-fluoro-4-(iodomethyl)cyclopentoxy]-dimethyl-silane (CAS 942143-86-4), a certified reference material (molecular formula C12H24FIOSi, MW 358.31 g/mol) for analytical method development and quality control.
The molecular framework of tert-butyl-[rel-(1R,2R,4S)-2-fluoro-4-(iodomethyl)cyclopentoxy]-dimethyl-silane (C12H24FIOSi) is characterized by a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), tert-butyl-[rel-(1R,2R,4S)-2-fluoro-4-(iodomethyl)cyclopentoxy]-dimethyl-silane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H24FIOSi |
| Molecular Weight | 358.31 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/I-containing |
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