(E)-N-(4-((tert-Butyldimethylsilyl)oxy)benzylidene)-4-fluoroaniline CAS 942485-61-2
| CAS No. | 942485-61-2 |
| Molecular Formula | C19H24FNOSi |
| Molecular Weight | 329.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(E)-N-(4-((tert-Butyldimethylsilyl)oxy)benzylidene)-4-fluoroaniline (CAS 942485-61-2), molecular formula C19H24FNOSi and molecular weight 329.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-N-(4-((tert-Butyldimethylsilyl)oxy)benzylidene)-4-fluoroaniline (C19H24FNOSi) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H24FNOSi |
| Molecular Weight | 329.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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