4-Chloroquinazoline-7-carboxylic acid CAS 942507-89-3
| CAS No. | 942507-89-3 |
| Molecular Formula | C9H15ClN2O2 |
| Molecular Weight | 218.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloroquinazoline-7-carboxylic acid (CAS 942507-89-3), molecular formula C9H15ClN2O2 and molecular weight 218.68 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloroquinazoline-7-carboxylic acid (C9H15ClN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloroquinazoline-7-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H15ClN2O2 |
| Molecular Weight | 218.68 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroquinazoline Standards
- 6-chloroquinazoline-2-carboxylic acid (CAS 1204390-45-3)
- 2-chloroquinazoline-7-carboxylic acid (CAS 1429422-30-9)
- Methyl 2-chloroquinazoline-6-carboxylate (CAS 1036755-96-0)
- Methyl 2-chloroquinazoline-8-carboxylate (CAS 1217269-81-2)
- Methyl 2-Chloroquinazoline-5-carboxylate (CAS 1221288-22-7)
- Methyl 4-Chloroquinazoline-5-carboxylate (CAS 1260890-93-4)
- Methyl 4-chloroquinazoline-2-carboxylate (CAS 1284130-45-5)
- 7-Chloroquinazoline-4-acetic Acid (CAS 1783794-98-8)
Recommended Standards
- 4-Chloro-N-(pyridin-4-ylmethyl)aniline (CAS 29083-47-4)
- 4-Ethyl-1-naphthoyl chloride (CAS 824430-39-9)
- 4-Chloro-N-(pyridin-3-ylmethyl)aniline (CAS 29083-43-0)
- 5-Chloro-6,7,8,9-tetrahydrobenzo[b][1,8]naphthyridine (CAS 267220-23-5)
- N-(1-Hydroxy-2-methylpropan-2-yl)formamide (CAS 682-85-9)
- 5-chloro-4-methyl-2-(pyrrolidin-3-yl)phenol hydrobromide (CAS 1955531-91-5)
- 6-Amino-3-cyclopropoxypicolinaldehyde (CAS 1243471-56-8)
- Atogepant impurity 2 (CAS 1456803-45-4)
- S-tert-Leucine N-methylamide (CAS 89226-12-0)
- 2-(4-Fluoro-3-nitrophenylsulfonamido)acetic acid (CAS 1041573-13-0)
- 2'-Chloro-N-cyclopentyl-5'H-spiro[cyclobutane-1,6'-thieno[2,3-d]pyrimidin]-4'-amine (CAS 1956379-77-3)
- 4-(Isopentyloxy)butane-1-sulfonyl chloride (CAS 1344240-73-8)
- 4-(4-(Trifluoromethyl)phenyl)oxazolidin-2-one (CAS 1486650-17-2)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com